Reference table · Labels read Aug 15, 2026
HRT dosage chart
This is a reference table, not medical advice. It documents what the FDA labels say and it will never tell you what to take. Below are 36 labelled strengths across 14FDA-approved estradiol, progesterone and testosterone products, each with the starting dose stated on that product's own label, the label's effective date, and a link to the label on DailyMed. Estradiol patches run 0.025 to 0.1 mg per day, oral estradiol comes as 0.5, 1 and 2 mg tablets, and the vaginal inserts and the ring are dosed in micrograms rather than milligrams.
The last column of each section is the part no drug reference carries: which telehealth providers on our roster actually dispense that delivery form, read from their own published formularies. Every strength and every starting-dose sentence here was read off a DailyMed Structured Product Label on Aug 15, 2026. Nothing was inferred from a drug class and nothing was carried over from a review article.
Estradiol
Patch
| Product | Labelled strengths | What the label says to start with | Label date |
|---|---|---|---|
| Vivelle-Dotestradiol transdermal systemSandoz Inc |
| “Start therapy with Vivelle-Dot 0.0375 mg per day applied to the skin twice weekly.”For moderate to severe vasomotor symptoms due to menopause. Twice weekly.The same label states a different start for prevention of postmenopausal osteoporosis: “Start therapy with Vivelle-Dot 0.025 mg/day”. | Nov 17, 2023Strengths from: Dosage Forms and Strengths |
| Minivelleestradiol transdermal systemNoven Therapeutics, LLC |
| “Start therapy with MINIVELLE 0.0375 mg per day applied to the skin twice weekly.”For moderate to severe vasomotor symptoms due to menopause. Twice weekly.The same label states a different start for prevention of postmenopausal osteoporosis: “Start therapy with MINIVELLE 0.025 mg per day applied to the skin twice weekly”. | Jul 31, 2026Strengths from: Dosage Forms and Strengths |
| Climaraestradiol transdermal systemBayer HealthCare Pharmaceuticals Inc. |
| “Start therapy with Climara 0.025 mg per day applied to the skin once-weekly.”For moderate to severe vasomotor symptoms due to menopause. Once weekly. | Mar 26, 2026Strengths from: Dosage Forms and Strengths |
Providers on our roster that dispense this form
A provider listed here prescribes this delivery form. It does not follow that it stocks the branded product in the table above, and most dispense a generic equivalent. Prices are on each review page and in the verified price table.
Gel
| Product | Labelled strengths | What the label says to start with | Label date |
|---|---|---|---|
| EstroGel 0.06%estradiol gel, meteredAscend Therapeutics US, LLC |
| “EstroGel 0.06% 1.25 g per day is the single approved dose for the treatment of moderate to severe vasomotor symptoms due to menopause. The lowest effective dose of EstroGel 0.06% for this indication has not been determined.”For moderate to severe vasomotor symptoms due to menopause. Once daily, applied to the arm. | May 29, 2026Strengths from: Dosage Forms and Strengths |
| Elestrinestradiol gel, meteredViatris Specialty LLC |
| “Start therapy with one pump per day (0.87 grams per day, which contains 0.52 mg of estradiol).”For moderate to severe vasomotor symptoms due to menopause. Once daily, applied to the upper arm. | Dec 15, 2023Strengths from: Dosage and Administration |
| Divigel 0.1%estradiol gelVertical Pharmaceuticals, LLC |
| “Daily administration of 0.25 to 1.25 grams of Divigel to the right or left upper thigh on alternating days. Women should be started with the lowest effective dose and the dose should be evaluated periodically.”For moderate to severe vasomotor symptoms due to menopause. Once daily, alternating thighs. | Feb 27, 2026Strengths from: Dosage Forms and Strengths |
Providers on our roster that dispense this form
A provider listed here prescribes this delivery form. It does not follow that it stocks the branded product in the table above, and most dispense a generic equivalent. Prices are on each review page and in the verified price table.
Spray
| Product | Labelled strengths | What the label says to start with | Label date |
|---|---|---|---|
| Evamistestradiol transdermal sprayPadagis US LLC |
| “Start Evamist therapy with one spray of Evamist per day.”For moderate to severe vasomotor symptoms due to menopause. Once daily each morning, to the inner forearm. | Oct 29, 2024Strengths from: Dosage Forms and Strengths |
Providers on our roster that dispense this form
A provider listed here prescribes this delivery form. It does not follow that it stocks the branded product in the table above, and most dispense a generic equivalent. Prices are on each review page and in the verified price table.
Pill or tablet
| Product | Labelled strengths | What the label says to start with | Label date |
|---|---|---|---|
| Estradiol Tablets, USPestradiolTeva Pharmaceuticals USA, Inc. |
| “The usual initial dosage range is 1 to 2 mg daily of estradiol adjusted as necessary to control presenting symptoms.”For moderate to severe vasomotor symptoms and vulvar and vaginal atrophy associated with the menopause. Once daily, administered cyclically (for example 3 weeks on and 1 week off). | Feb 1, 2024Strengths from: Description and How Supplied |
Providers on our roster that dispense this form
A provider listed here prescribes this delivery form. It does not follow that it stocks the branded product in the table above, and most dispense a generic equivalent. Prices are on each review page and in the verified price table.
Vaginal
| Product | Labelled strengths | What the label says to start with | Label date |
|---|---|---|---|
| Estrace Creamestradiol vaginal cream USP 0.01%Allergan, Inc. |
| “The usual dosage range is 2 to 4 g (marked on the applicator) daily for one or two weeks, then gradually reduced to one half initial dosage for a similar period. A maintenance dosage of 1 g, one to three times a week, may be used after restoration of the vaginal mucosa has been achieved.”For vulvar and vaginal atrophy associated with the menopause. Daily at first, then tapered. | May 29, 2024Strengths from: Description |
| Vagifemestradiol vaginal insertsNovo Nordisk |
| “Administer Vagifem intravaginally using the supplied applicator: 1 insert daily for 2 weeks, followed by 1 insert twice weekly.”For atrophic vaginitis due to menopause. Daily for 2 weeks, then twice weekly. | Feb 10, 2025Strengths from: Dosage Forms and Strengths |
| Imvexxyestradiol vaginal insertsMayne Pharma LLC |
| “Generally, start therapy with the IMVEXXY 4 mcg dosage strength administered intravaginally. Administer 1 insert daily at approximately the same time for 2 weeks, followed by 1 insert twice weekly, every three to four days.”For moderate to severe dyspareunia, a symptom of vulvar and vaginal atrophy, due to menopause. Daily for 2 weeks, then twice weekly. | Sep 16, 2025Strengths from: Dosage Forms and Strengths |
| Estringestradiol vaginal systemPfizer Laboratories Div Pfizer Inc |
| “One ESTRING is to be inserted as deeply as possible into the upper one-third of the vaginal vault. The ring is to remain in place continuously for three months, after which it is to be removed and, if appropriate, replaced by a new ring.”For urogenital symptoms of postmenopausal atrophy. One ring every 90 days. | Apr 23, 2026Strengths from: How Supplied |
Providers on our roster that dispense this form
A provider listed here prescribes this delivery form. It does not follow that it stocks the branded product in the table above, and most dispense a generic equivalent. Prices are on each review page and in the verified price table.
Progesterone
A note on the provider column here, because it looks thin and the reason matters. 8providers on the women's wing sell a progesterone product and only 1name its delivery route in the product string. We will not borrow a route from a provider's estradiol line to fill the gap, because that manufactures products nobody sells. The blank is their disclosure gap and we print it rather than covering it.
Pill or tablet
| Product | Labelled strengths | What the label says to start with | Label date |
|---|---|---|---|
| Prometriumprogesterone, USP capsulesAcertis Pharmaceuticals, LLC |
| “PROMETRIUM Capsules should be given as a single daily dose at bedtime, 200 mg orally for 12 days sequentially per 28-day cycle, to a postmenopausal woman with a uterus who is receiving daily conjugated estrogens tablets.”For prevention of endometrial hyperplasia. At bedtime, 12 days per 28-day cycle. | Jul 23, 2026Strengths from: How Supplied |
Providers on our roster that dispense this form
A provider listed here prescribes this delivery form. It does not follow that it stocks the branded product in the table above, and most dispense a generic equivalent. Prices are on each review page and in the verified price table.
Testosterone
Injection
| Product | Labelled strengths | What the label says to start with | Label date |
|---|---|---|---|
| Depo-Testosteronetestosterone cypionate injectionPharmacia & Upjohn Company LLC |
| “For replacement in the hypogonadal male, 50 to 400 mg should be administered every two to four weeks.”For replacement in the hypogonadal male. Every two to four weeks, intramuscular. | Sep 29, 2025Strengths from: How Supplied |
Providers on our roster that dispense this form
A provider listed here prescribes this delivery form. It does not follow that it stocks the branded product in the table above, and most dispense a generic equivalent. Prices are on each review page and in the verified price table.
Why there is no estrogen or testosterone level chart on this page
A serum hormone reference range belongs to the assay and the laboratory that ran it, and it is printed on your lab report. It is not on any drug label, so it is not on this page. Ask the lab that ran your panel for its own range, and read your result against that.
There is a second reason specific to perimenopause. A single estradiol or FSH reading is an unreliable guide in the years before the final period, because the levels swing across and within cycles. Treatment decisions in that window are usually made on symptoms and cycle history rather than on one blood draw, which is why our symptom checker runs a validated symptom instrument and not a lab-range lookup.
How to read this chart
- The starting dose belongs to an indication. Several of these labels state one starting dose for hot flashes and a different one for osteoporosis prevention. Both are printed above with the indication attached, because a dose quoted without its indication is a number with no meaning.
- Strengths are not interchangeable across routes. A 0.05 mg per day patch and a 0.5 mg tablet are not the same amount of drug reaching you, because the patch bypasses first-pass liver metabolism and the tablet does not. Route conversion is a clinical calculation and this table does not attempt one.
- The vaginal inserts and the ring are dosed in micrograms. Vagifem is 10 mcg and Imvexxy starts at 4 mcg, against 500 to 2,000 mcg in a systemic tablet. Estrace Cream is the exception in this group and is labelled in milligrams, at 0.1 mg of estradiol per gram of cream. Local products are prescribed for local symptoms and are generally considered separately from systemic therapy.
- Check the label date.The dates above span several years. Some of these labels predate the FDA's November 2025 boxed-warning removal and the February 2026 approved labeling changes, so a boxed warning still printed on an older posted label is not evidence of current FDA policy. What actually changed.
- Generic equivalents carry the same labelled strengths. Most providers dispense a generic rather than the brand named here, and the approved strengths are the same. The brand is named because that is the label we read.
Sources
Every label below was pulled as a DailyMed Structured Product Label and read directly on Aug 15, 2026. Reading the structured XML rather than the rendered page is deliberate: a partially rendered page has produced a false reading for us before, and the setid in each link is the stable identifier for re-checking any number here.
- Vivelle-Dot (estradiol transdermal system), Sandoz Inc · SPL effective Nov 17, 2023
- Minivelle (estradiol transdermal system), Noven Therapeutics, LLC · SPL effective Jul 31, 2026
- Climara (estradiol transdermal system), Bayer HealthCare Pharmaceuticals Inc. · SPL effective Mar 26, 2026
- EstroGel 0.06% (estradiol gel, metered), Ascend Therapeutics US, LLC · SPL effective May 29, 2026
- Elestrin (estradiol gel, metered), Viatris Specialty LLC · SPL effective Dec 15, 2023
- Divigel 0.1% (estradiol gel), Vertical Pharmaceuticals, LLC · SPL effective Feb 27, 2026
- Evamist (estradiol transdermal spray), Padagis US LLC · SPL effective Oct 29, 2024
- Estradiol Tablets, USP (estradiol), Teva Pharmaceuticals USA, Inc. · SPL effective Feb 1, 2024
- Estrace Cream (estradiol vaginal cream USP 0.01%), Allergan, Inc. · SPL effective May 29, 2024
- Vagifem (estradiol vaginal inserts), Novo Nordisk · SPL effective Feb 10, 2025
- Imvexxy (estradiol vaginal inserts), Mayne Pharma LLC · SPL effective Sep 16, 2025
- Estring (estradiol vaginal system), Pfizer Laboratories Div Pfizer Inc · SPL effective Apr 23, 2026
- Prometrium (progesterone, USP capsules), Acertis Pharmaceuticals, LLC · SPL effective Jul 23, 2026
- Depo-Testosterone (testosterone cypionate injection), Pharmacia & Upjohn Company LLC · SPL effective Sep 29, 2025
Adverse-reaction rates from two of these same labels, with the placebo column beside every number, are on our estradiol patch side effects and progesterone side effects pages.
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This is a reference table of published label information, not medical advice. It records what FDA-approved labels state. It does not recommend a product, a strength or a starting dose to anyone, and no dose on this page should be started, changed or stopped without a licensed clinician who knows your history. HRT Picks is not a medical provider and has no role in your care. Reviewed by Iacob Pastina.
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